Volume 2, Issue 3, June 2014, Page: 17-26
Synthesis, Magnetic, Spectral and Biological Studies of Copper(II) Complexes of 4-Benzoyl-3-Methyl-1-Phenyl-2-Pyrazolin-5-One N(4)-Substituted Thiosemicarbazones
Ayman K. El-Sawaf, Chemistry Department, College of Science and Humanity Studies, Salman bin Abdulaziz University, AlKharj, KSA.11942; Chemistry Department, Faculty of Science, Minoufiya University, Shebin El-Kom, Egypt
Amal Abdel Fatah Nassar, Chemistry Department, College of Education for Girls, Salman bin Abdulaziz University, KSA
El-Sayed El-Samanody, Chemistry Department, College of Science and Humanity Studies, Salman bin Abdulaziz University, AlKharj, KSA.11942; Chemistry Department, Faculty of Science, Minoufiya University, Shebin El-Kom, Egypt
Received: Aug. 11, 2014;       Accepted: Aug. 18, 2014;       Published: Aug. 30, 2014
DOI: 10.11648/j.sjc.20140203.12      View  3874      Downloads  318
Abstract
The synthesis and characterization of copper(II) complexes with 4-benzoyl-3-methyl-1-phenyl-2-pyrazolin-5-one thiosemicarbazone and N(4)-substituted thiosemicarbazones are reported. Elemental analysis, molar conductivities, magnetic measurements and spectral (i.r., electronic, e.s.r., and n.m.r.) studies have been used to characterize the complexes. The i.r. spectra show that the thiosemicarbazones behave as bidentate ligands, either in the thione or thiolato form. Stereochemistries are proposed for the complexes on the basis of spectral and magnetic studies. Both the thiosemicarbazones and their complexes show either modest or no growth inhibitory activity against Aspergillus niger and Paecilomyces variotii.
Keywords
Synthesis, Thiosemicarbazones, Characterization, Complexes, Stereochemistries, Antifungal
To cite this article
Ayman K. El-Sawaf, Amal Abdel Fatah Nassar, El-Sayed El-Samanody, Synthesis, Magnetic, Spectral and Biological Studies of Copper(II) Complexes of 4-Benzoyl-3-Methyl-1-Phenyl-2-Pyrazolin-5-One N(4)-Substituted Thiosemicarbazones, Science Journal of Chemistry. Vol. 2, No. 3, 2014, pp. 17-26. doi: 10.11648/j.sjc.20140203.12
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